Hurler Syndrome: a Biochemically Confirmed Case in Dominican Republic

USAID/Dominican Republic Strategic Plan

Hurler Syndrome ( Severe Type ) - A Rare Case Report

Hurler syndrome is one of the rare genetic disorders involving disturbances in mucopolysaccharide metabolism resulting in their increased accumulation in the lysosomes. This leads to a progressive disorder involving multiple organs that often results in death by second decade of life. This disease, which has several oral and dental manifestations, is first diagnosed on the basis of clinical fin...

Helminths from a stranded manatee in the Dominican Republic.

Endangered West Indian manatees (Trichechus manatus) are known to be parasitized by a number of helminths and ectoparasites. Records of parasitic associations exist for Florida, Mexico, Guyana, Brazil, Cuba and recently for Puerto Rico. Parasites of manatees in other Caribbean areas have not been documented, particularly from Hispaniola. We report on the occurrence of a species of nematode and ...

Malaria and Travel to the Dominican Republic

To the Editor: The rise in international travel to malaria-endemic areas in recent years has been followed by an increase in the number of cases diagnosed in countries where malaria is not endemic (1). Tourist areas of the Dominican Republic have traditionally been considered to be low risk for malaria transmission. However, over the past few years, sporadic descriptions of imported falciparum ...

Glaucoma in a case of Hurler disease.

The electron microscopic appearances of the corneoscleral and iris tissue removed at operation from a child with Hurler disease and glaucoma showed distinctive swollen cells with intracellular inclusions similar to those which are observed in other tissues in these patients and which are due to abnormal lysosomal storages of mucopolysaccharides. Some recent observations on the possible relation...